{"id":544,"date":"2020-02-17T09:18:39","date_gmt":"2020-02-17T09:18:39","guid":{"rendered":"https:\/\/ibit.webs.upv.es\/?page_id=544"},"modified":"2020-02-17T09:33:36","modified_gmt":"2020-02-17T09:33:36","slug":"intramuralciber-bbnmieloma2019","status":"publish","type":"page","link":"https:\/\/ibit.webs.upv.es\/index.php\/showcase\/intramuralciber-bbnmieloma2019\/","title":{"rendered":"Intramural CIBER-BBN Project Myeloma 2019"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">In this project we aim to develop a 3D culture environment for myeloma cells,  to optimize an environment in which interaction between relevant cell types can take place mimicking the bone marrow of a multiple myeloma patient.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The system is based on microgels that consist of synthetic microparticles (in the order of 5 to 15 microns diamneter), coated with different biomolecules such as fibronectin, collagen type I, hyaluronic acid or chondroitin sulphate. These are proteins or polysaccharides characteristic of the extracellular matrix of many tissues. As a proof of concept in this project, we will work on the culture of multiple myeloma (MM) cells in an environment able to support tumour cells with the same functional activity and markers as in the natural niche. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The project coordinates activites at our group with another group at CIBER-BBN that also specialises in biomaterials engieering (IP Ram\u00f3n Mart\u00ednez M\u00e1\u00f1ez) and a group at CIBERONC (IP Amparo Sempere Talens) with clinicians experts in the treament and clinical research of MM. <\/p>\n","protected":false},"excerpt":{"rendered":"<p>In this project we aim to develop a 3D culture environment for myeloma cells, to optimize an environment in which&hellip;<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":343,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_jetpack_hide_featured_image":false,"_jetpack_featured_image_duplicate_dismissed":0,"footnotes":""},"class_list":["post-544","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Intramural CIBER-BBN Project Myeloma 2019 - IBIT<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ibit.webs.upv.es\/index.php\/showcase\/intramuralciber-bbnmieloma2019\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Intramural CIBER-BBN Project Myeloma 2019 - IBIT\" \/>\n<meta property=\"og:description\" content=\"In this project we aim to develop a 3D culture environment for myeloma cells, to optimize an environment in which&hellip;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/ibit.webs.upv.es\/index.php\/showcase\/intramuralciber-bbnmieloma2019\/\" \/>\n<meta property=\"og:site_name\" content=\"IBIT\" \/>\n<meta property=\"article:modified_time\" content=\"2020-02-17T09:33:36+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:site\" content=\"@CBIT_upv\" \/>\n<meta name=\"twitter:label1\" content=\"Tiempo de lectura\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minuto\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/ibit.webs.upv.es\\\/index.php\\\/showcase\\\/intramuralciber-bbnmieloma2019\\\/\",\"url\":\"https:\\\/\\\/ibit.webs.upv.es\\\/index.php\\\/showcase\\\/intramuralciber-bbnmieloma2019\\\/\",\"name\":\"Intramural CIBER-BBN Project Myeloma 2019 - IBIT\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/ibit.webs.upv.es\\\/#website\"},\"datePublished\":\"2020-02-17T09:18:39+00:00\",\"dateModified\":\"2020-02-17T09:33:36+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/ibit.webs.upv.es\\\/index.php\\\/showcase\\\/intramuralciber-bbnmieloma2019\\\/#breadcrumb\"},\"inLanguage\":\"es\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/ibit.webs.upv.es\\\/index.php\\\/showcase\\\/intramuralciber-bbnmieloma2019\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/ibit.webs.upv.es\\\/index.php\\\/showcase\\\/intramuralciber-bbnmieloma2019\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/ibit.webs.upv.es\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Projects Showcase\",\"item\":\"https:\\\/\\\/ibit.webs.upv.es\\\/index.php\\\/showcase\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Intramural CIBER-BBN Project Myeloma 2019\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/ibit.webs.upv.es\\\/#website\",\"url\":\"https:\\\/\\\/ibit.webs.upv.es\\\/\",\"name\":\"Centre for Biomaterials and Tissue Engineering - UPV\",\"description\":\"Research Institute for Biomaterials and Tissue Engineering at the Universitat Polit\u00e8cnica de Val\u00e8ncia\",\"publisher\":{\"@id\":\"https:\\\/\\\/ibit.webs.upv.es\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/ibit.webs.upv.es\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"es\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/ibit.webs.upv.es\\\/#organization\",\"name\":\"Centre for Biomaterials and Tissue Engineering - UPV\",\"url\":\"https:\\\/\\\/ibit.webs.upv.es\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"es\",\"@id\":\"https:\\\/\\\/ibit.webs.upv.es\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/ibit.webs.upv.es\\\/wp-content\\\/uploads\\\/2019\\\/10\\\/logo-CBIT-grande.png\",\"contentUrl\":\"https:\\\/\\\/ibit.webs.upv.es\\\/wp-content\\\/uploads\\\/2019\\\/10\\\/logo-CBIT-grande.png\",\"width\":2268,\"height\":689,\"caption\":\"Centre for Biomaterials and Tissue Engineering - UPV\"},\"image\":{\"@id\":\"https:\\\/\\\/ibit.webs.upv.es\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/x.com\\\/CBIT_upv\"]}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Intramural CIBER-BBN Project Myeloma 2019 - IBIT","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/ibit.webs.upv.es\/index.php\/showcase\/intramuralciber-bbnmieloma2019\/","og_locale":"es_ES","og_type":"article","og_title":"Intramural CIBER-BBN Project Myeloma 2019 - IBIT","og_description":"In this project we aim to develop a 3D culture environment for myeloma cells, to optimize an environment in which&hellip;","og_url":"https:\/\/ibit.webs.upv.es\/index.php\/showcase\/intramuralciber-bbnmieloma2019\/","og_site_name":"IBIT","article_modified_time":"2020-02-17T09:33:36+00:00","twitter_card":"summary_large_image","twitter_site":"@CBIT_upv","twitter_misc":{"Tiempo de lectura":"1 minuto"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/ibit.webs.upv.es\/index.php\/showcase\/intramuralciber-bbnmieloma2019\/","url":"https:\/\/ibit.webs.upv.es\/index.php\/showcase\/intramuralciber-bbnmieloma2019\/","name":"Intramural CIBER-BBN Project Myeloma 2019 - IBIT","isPartOf":{"@id":"https:\/\/ibit.webs.upv.es\/#website"},"datePublished":"2020-02-17T09:18:39+00:00","dateModified":"2020-02-17T09:33:36+00:00","breadcrumb":{"@id":"https:\/\/ibit.webs.upv.es\/index.php\/showcase\/intramuralciber-bbnmieloma2019\/#breadcrumb"},"inLanguage":"es","potentialAction":[{"@type":"ReadAction","target":["https:\/\/ibit.webs.upv.es\/index.php\/showcase\/intramuralciber-bbnmieloma2019\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/ibit.webs.upv.es\/index.php\/showcase\/intramuralciber-bbnmieloma2019\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/ibit.webs.upv.es\/"},{"@type":"ListItem","position":2,"name":"Projects Showcase","item":"https:\/\/ibit.webs.upv.es\/index.php\/showcase\/"},{"@type":"ListItem","position":3,"name":"Intramural CIBER-BBN Project Myeloma 2019"}]},{"@type":"WebSite","@id":"https:\/\/ibit.webs.upv.es\/#website","url":"https:\/\/ibit.webs.upv.es\/","name":"Centre for Biomaterials and Tissue Engineering - UPV","description":"Research Institute for Biomaterials and Tissue Engineering at the Universitat Polit\u00e8cnica de Val\u00e8ncia","publisher":{"@id":"https:\/\/ibit.webs.upv.es\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/ibit.webs.upv.es\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"es"},{"@type":"Organization","@id":"https:\/\/ibit.webs.upv.es\/#organization","name":"Centre for Biomaterials and Tissue Engineering - UPV","url":"https:\/\/ibit.webs.upv.es\/","logo":{"@type":"ImageObject","inLanguage":"es","@id":"https:\/\/ibit.webs.upv.es\/#\/schema\/logo\/image\/","url":"https:\/\/ibit.webs.upv.es\/wp-content\/uploads\/2019\/10\/logo-CBIT-grande.png","contentUrl":"https:\/\/ibit.webs.upv.es\/wp-content\/uploads\/2019\/10\/logo-CBIT-grande.png","width":2268,"height":689,"caption":"Centre for Biomaterials and Tissue Engineering - UPV"},"image":{"@id":"https:\/\/ibit.webs.upv.es\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/x.com\/CBIT_upv"]}]}},"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/ibit.webs.upv.es\/index.php\/wp-json\/wp\/v2\/pages\/544","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ibit.webs.upv.es\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/ibit.webs.upv.es\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/ibit.webs.upv.es\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/ibit.webs.upv.es\/index.php\/wp-json\/wp\/v2\/comments?post=544"}],"version-history":[{"count":3,"href":"https:\/\/ibit.webs.upv.es\/index.php\/wp-json\/wp\/v2\/pages\/544\/revisions"}],"predecessor-version":[{"id":549,"href":"https:\/\/ibit.webs.upv.es\/index.php\/wp-json\/wp\/v2\/pages\/544\/revisions\/549"}],"up":[{"embeddable":true,"href":"https:\/\/ibit.webs.upv.es\/index.php\/wp-json\/wp\/v2\/pages\/343"}],"wp:attachment":[{"href":"https:\/\/ibit.webs.upv.es\/index.php\/wp-json\/wp\/v2\/media?parent=544"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}